Thursday, May 14, 2020

Why The Cancer Experts Support Gene Testing To Diagnose...

Cancer Experts Support Gene Testing to Diagnose Cancer Gene testing offers extraordinary benefits for diagnosing and treating various forms of cancer. DNA tests can help guide physicians to the best treatment therapies, and more than 31,000 NHS patients have already had their entire genome sequenced, which many medical professionals suggest should become a standardized medical practice as routine as blood tests or biopsies. [1] Why DNA Holds the Keys to Effective Cancer Treatment International scientists recently made a watershed breakthrough in medical technology that promises to generate paradigm changes in medical treatments. More than a decade ago, scientists at the Human Genome Project finally mapped the genetic blueprint of Homo†¦show more content†¦Custom antibodies--when attached to cancer-killing drugs--can be engineered to attach to diseased cancer cells while bypassing healthy tissue. Genomic differentiation allows this kind of ADC therapy to be targeted to each patient based on various genomic characteristics. By combining the power of antibodies with the cancer-destroying abilities of cytotoxic drugs, these therapies can generate better results than flooding the body with systemic chemo treatments that often generate unpleasant side effects that include killing healthy tissue. Stable Linkers Another area thats important in developing cancer treatments is providing a stable link between the antibody and cytotoxic cancer-killing agent. The more stable the ADC linker, the more effective the cancer treatment will be. Secure links ensure that less of the cancer-killing payload falls off in the circulatory system before delivering its therapeutic benefit. Different chemical motifs are used for linkers, and these include hydrazones, peptides and disulfides for hydrazones, peptides and disulfides for cleavable links and thioethers for noncleavable links. 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